Advanced analytical strategies for recombinant therapeutic proteins.
نویسنده
چکیده
Therapeutic proteins produced using recombinant DNA technologies are generally complex, heterogeneous, and subject to a variety of enzymatic or chemical modifications during expression, purification, and long-term storage. Hence the analytical strategies for characterization, quantitation, purity assay and evaluation of the biological activity of recombinant proteins still represent a big challenge and a matter for debate.
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ورودعنوان ژورنال:
- Current pharmaceutical biotechnology
دوره 12 10 شماره
صفحات -
تاریخ انتشار 2011